OGC P46 Positive Circumferential margins are associated with poorer survival following surgery in gastro-oesophageal junctional cancers

Abstract Background Adenocarcinoma of the gastro-oesophageal junction (GOJ) remains a significant clinical problem that is increasing in incidence and associated with poor prognosis. The aim this study to determine effects resection margins on survival recurrence. Methods A retrospective was conducted at our hospital from March 2001 till December 2022. All patients had oesophagectomy for junctional adenocarcinoma were included study. Demography, staging, margins, type neo-adjuvant chemotherapy data collected. Results Over study, 174 Gastro-oesophageal adenocarcinoma. 42 circumferential positive 132 negative margins. median 18 months 31 P value <0.001 There no longitudinal enough calculate any statical analysis recurrence 13.4 26.8 0.003 Conclusions presence margin tumour will significantly affect rate rate.